Crossword Puzzle Crimefighter of early '60s TV

Clue: Crimefighter of early '60s TV

Leaves the office early? (RESIGNS with 7 letters)
Leaves early, as an office (VACATES with 7 letters)
Early Atari offering (PONG with 4 letters)
Spy's reaction to an early retirement offer? (DESKJOBINTERESTSAGENT with 21 letters)
Early TV offering (GMA with 3 letters)
Early offspring (CAIN with 4 letters)
Early Microsoft offering (DOS with 3 letters)
Reserve officially (BOOK with 4 letters)
Early medico (HIPPOCRATES with 11 letters)
Bond offerer, e.g. (ISSUER with 6 letters)